Paper published in Nature Microbiology- ‘Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells’

The latest paper from the Jeffrey Lab in Nature Microbiology.

In the paper we show for the first time that RNA interference (RNAi) – an antiviral mechanism known to be used by plants and lower organisms – is active in the response of human cells to some important viruses. We document both the production of RNAi molecules in human cells infected with the influenza A virus and the suppression of RNAi defense by a viral protein known to block the process in a common animal model.